1) Diabetes type 2 is caused by insulin resistance in body cells.
2) Insulin is a hormone secreted by pancreas.
3) Insulin resistance results in less absorption of glucose by cells and consequently its higher concentration in blood.
4) Insulin resistance is due to another hormone called cortisol.
5) Cortisol is produced in the cortex of adrenal glands, located on kidneys.
6) Cortisol production is regulated by adrenocorticotropic hormone (ACTH).
7) Adrenocorticotropic hormone (ACTH) is produced by anterior pituitary gland.
8) Anterior pituitary gland is stimulated by corticotropin-releasing hormone (CRH).
9) Corticotropin-releasing hormone (CRH) is released from the hypothalamus.
10) The hypothalamus is located on the undersurface of the brain. It lies just below the thalamus and above the pituitary gland, to which it is attached by a stalk. It is an extremely complex part of the brain containing many regions with highly specialised functions.
11) The hypothalamus is considered as the key brain region for the control of homeostasis.
12) Homeostasis refers to maintainance of a state of internal balance and physical wellbeing in spite of internal changes or outside factors.
13) Hypothalamic dysfunction may occur due to head injuries, growth hormone deficiency, birth defects involving the brain or hypothalamus, tumors in or around the hypothalamus, eating disorders, autoimmune conditions, surgery involving the brain and artificial light radiations.
14) When the body is exposed only to the natural light of the sun, the hypothalamus area of the brain sets its sleep patterns according to when it is light outside and to when it is dark.
15) When it starts getting dark outside, the hypothalamus signals to the body to start creating sleep hormones, like melatonin, and to drop the human's body temperature to prepare for sleep.
16) In the morning, when light is sensed, the body is told to warm up and to produce hormones, like cortisol, that wake the body up. When artificial light is added to a human's day, the body's natural rhythms become confused.
17) So all artificial light, including LEDs, fluorescent bulbs, incandescent bulbs, cell phones, computers and televisions can interrupt normal sleep patterns, confuse hypothalamus, that disturbs homoeostasis, high cortisol production, more insulin resistance and type 2 diabetes.
18) The same kind of other mechanisms may also be responsible for hypertension, cardiovascular problems and kidney problems.
19) Lifestyle changes, bad food habits, junk food, cool drinks, smoking, alcoholic consumption, drug addiction, sedentary lifestyle, less physical activities, less sleep, belly fat, obesity, seasonal changes and climate change my aggravate the problems.
20) The reason for sudden unabated raise in diabetes type 2 might be triggered by mobile addiction also!
